Maintenance therapy in NSCLC: why? To whom? Which agent?
نویسندگان
چکیده
منابع مشابه
Maintenance therapy in NSCLC: why? To whom? Which agent?
Maintenance therapy is emerging as a treatment strategy in the management of advanced non small cell lung cancer (NSCLC). Initial trials addressing the question of duration of combination chemotherapy failed to show any overall survival benefit for the prolonged administration over a fixed number of cycles with an increased risk for cumulative toxicity. Nowadays several agents with different wa...
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Nowadays, advanced non-small cell lung cancer (NSCLC) is still an incurable disease. However, recent researches on maintenance therapy have led to considerable progress. Recently, pemetrexed and erlotinib have been approved for maintenance chemotherapy by both the U.S. Food and Drug Administration and European Medicines Agency. However, there are not adequate data to support the maintenance the...
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INTRODUCTION In the past few years many trials have evaluated the use of maintenance therapy in the treatment of NSCLC stage IV. Both switch as well as continuation maintenance show an improved PFS and overall survival. HRQoL data was only partially published. The aim of this article is to review the published effects of maintenance therapy on HRQoL. METHODS Two PubMed searches were performed...
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I n 2000, the American Board of Medical Specialties (ABMS) mandated all 24 specialty affiliates to limit board certification (BC) duration to 10 years. This occurred against initial opposition of several of the affiliates, as the utility, financial, and time impositions, as well as the basic need for such imposition, were openly questioned. Given the threat of losing the ‘franchise’ if not adhe...
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This paper proposes and estimates a static non-parametric transferable utility model of the marriage market. The model rationalizes the standard interpretation of marriage rate regressions as well as pointing out its limitations. The model was used to estimate US marital behavior in 1971/72 and 1981/82. The estimates show that the gains to marriage for young adults fell substantially over the d...
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ژورنال
عنوان ژورنال: Journal of Experimental & Clinical Cancer Research
سال: 2011
ISSN: 1756-9966
DOI: 10.1186/1756-9966-30-50